Longevity / discovery / 3 MIN READ
Rapamycin: From Transplant Drug to Longevity Bet
Early Phase-2 trials show measurable effects on immune aging. What does that mean for healthy adults?
Reality 55 /100
Hype 60 /100
Impact 75 /100
Explanation
An old transplant medicine is being tested on thousands of healthy people. Results look promising but warrant caution.
The PEARL trial reports an 8-15% improvement in immune response in older adults on low-dose rapamycin. mTOR inhibition as an anti-aging strategy is still debated due to side effects.
Reality meter
Longevity Time horizon · mid term
Reality Score 55 / 100
Hype Risk 60 / 100
Impact 75 / 100
Source Quality 70 / 100
Community Confidence 50 / 100
Time horizon
Expected mid term
Community read
Community live aggregateIdle
Reality (article)55
Hype60
Impact75
Confidence50
Prediction Yes0%
Prediction votes0
Glossary
- mTOR
- Central signaling pathway for cell growth and aging.
- PEARL trial
- Crowd-funded Phase-2 rapamycin trial.
Sources
Prediction
Will at least three Phase-3 trials of rapamycin as an anti-aging therapy be running by 2030?
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